Responsable : Marie-Hélène VerlhacRechercheWe study the last stages of murine oogenesis, a process that terminates with the production of functional female gametes required for sexual reproduction. The last step of oogenesis, named meiotic maturation, corresponds to two successive asymmetric divisions without intervening DNA replication. Mammalian meiotic maturation takes place at puberty under periodical hormonal influence. It can be reproduced and followed in vitro on synchronized popul...